Current funded projects

We are currently supporting two one year research fellowships, find out more

We are currently supporting two one year research fellowships:

Alejandro Labastida Ramirez at the Department of Chronic Pain & Migraine in London

Study name: Estrogen-dependent sensitization of trigeminal neuropeptide signalling: interplay of migraine and temporomandibular joint disorder

Looking at the influence of oestrogen and its interaction with key neuropeptides involved in migraine

Eloisa Rubio at the Headache Group, Wolfson Centre for Age-Related Diseases, Kings College, London

Study name: Kisspeptin as a sexually dimorphic novel therapeutic target for migraine

Looking at how the hormone kisspeptin may be involved with migraine in the hope of developing new therapies for women with migraine

We recently funded a PhD studentship for a project that is being led by Dr Jan Hoffmann and Dr Philip Holland at the Institute of Psychiatry, Psychology and Neuroscience, King’s College London.

Neuroscientist Hannah Creeney was awarded a studentship to work on the project from 2019 ‘The neurophysiological role of amylin in migraine’.

Amylin is a neuropeptide that is known to have similar mechanisms to calcitonin gene-related peptide (CGRP), a neuropeptide that is released during migraine attacks and can increase the activation of the nerves that relay headache and facial pain signals to the brain. Amylin and CGRP bind to each other’s receptor and this research was looking at whether amylin’s actions on these receptors are relevant for migraine. The research aimed to determine if an increased understanding of amylin could lead to a new treatment for migraine.

Hannah Creeney with Dr Phil Holland and Dr Jan Hoffmann